ANESTHESIA VIDEO LECTURES

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Cerebral Perfusion Pressure


CBF = CPP/CVR

CPP = MAP - (higher of ICP or CVP)

• CPP <50 or >150mmHg ⟹ loss of cerebral autoregulation ⟹ flow   is pressure passive
↳ same as uterus

• EEG effects @37deg C:

‣ CPP <50mmHg ⟹ slowing EEG
‣ 25-40 ⟹ flat EEG
‣ <20mmHg ⟹ cell death if prolonged
" ↳ = <25ml/100g/min

• in head injured pt ie assumed ICP 20mmHg (no monitor):

‣ should keep CPP >70mmHg
‣ ie MAP >90mmHg
Location: United States

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