ANESTHESIA VIDEO LECTURES
Cerebral Perfusion Pressure CBF = CPP/CVR CPP = MAP - (higher of ICP or CVP) • CPP <50 or >150mmHg ⟹ loss of cerebral autoregulation ⟹ flow is pressure passive ↳ same as uterus • EEG effects @37deg C: ‣ CPP <50mmHg ⟹ slowing EEG ‣ 25-40 ⟹ flat EEG ‣ <20mmHg ⟹ cell death if prolonged " ↳ = <25ml/100g/min • in head injured pt ie assumed ICP 20mmHg (no monitor): ‣ should keep CPP >70mmHg ‣ ie MAP >90mmHg