One lung ventilation

-

 


One lung ventilation, keeping it simple

In this episode, our Host, Prof. Cesare Gregoretti will discuss with Dr Lorenzo Ball issues related to “One lung ventilation”. What makes one lung ventilation difficult? Which are the main indications for one lung ventilation in the operating room? How we achieve lung separation? Is there room for one lung ventilation in emergency setting in the ICU? Listen to this podcast and find out more on “One lung ventilation” and how to “keeping it simple”.




Comments

Post a Comment

Latest Updates

Popular posts from this blog

Danavorexton (TAK-925): A Promising Breakthrough in Combating Opioid-Induced Respiratory Depression

-
Danavorexton (TAK-925): A Promising Breakthrough in Combating Opioid-Induced Respiratory Depression Danavorexton (TAK-925): A Promising Breakthrough in Combating Opioid-Induced Respiratory Depression Opioids remain a cornerstone of pain management in clinical settings, yet their use is shadowed by life-threatening side effects, including respiratory depression and excessive sedation. A recent podcast episode from Anesthesiology ’s featured author series highlights a groundbreaking solution: danavorexton (TAK-925) , an orexin receptor 2 agonist that could revolutionize how we manage opioid-related complications. What Is Danavorexton (TAK-925)? Danavorexton is a selective agonist of the orexin-2 receptor (OX2R), a key player in regulating wakefulness and respiration. Orexins (also known as hypocretins) are neuropeptides produced in the hypothalamus that activate OX1R and OX2R receptors, influencing arousal, appetite, and...
Read more

Continuous vs. Bolus Norepinephrine for Post-Induction Hypotension

-
Continuous vs. Bolus Norepinephrine for Post-Induction Hypotension Continuous vs. Bolus Norepinephrine for Post-Induction Hypotension: A Landmark Trial Key Takeaway: Continuous infusion of norepinephrine offers no significant advantage over manual bolus administration in reducing post-induction hypotension in low-to-moderate risk noncardiac surgery patients, according to a randomized trial in the British Journal of Anaesthesia . Study Design Participants: 276 patients (261 analyzed) undergoing elective noncardiac surgery Interventions: Randomized to continuous infusion (target: 0.05 µg/kg/min) or manual boluses (10 µg) Monitoring: Intermittent oscillometric BP + blinded continuous finger-cuff monitoring Primary Endpoint: Area under MAP Key Findings Metric Continuous Infusion Bolus Administration Area under MA...
Read more

Anesthetic Mechanisms: Synergistic Interactions With Lipid Rafts and Voltage-Gated Sodium Channels

-
Image
Despite successfully utilizing anesthetics for over 150 years, the mechanism of action remains relatively unknown. Recent studies have shown promising results, but due to the complex interactions between anesthetics and their targets, there remains a clear need for further mechanistic research. We know that lipophilicity is directly connected to anesthetic potency since lipid solubility relates to anesthetic partition into the membrane. However, clinically relevant concentrations of anesthetics do not significantly affect lipid bilayers but continue to influence various molecular targets. Lipid rafts are derived from liquid-ordered phases of the plasma membrane that contain increased concentrations of cholesterol and sphingomyelin and act as staging platforms for membrane proteins, including ion channels. Although anesthetics do not perturb membranes at clinically relevant concentrations, they have recently been shown to target lipid rafts. In this review, we summarize current research...
Read more